Direct answer
Yes. US dollars are widely accepted for tourism services, permits, hotels, and safari payments, especially newer notes issued after 2013.
Recommended Uganda safari tours
Best
Seller
3 Day Uganda Gorilla Trekking Safari
You visit: Entebbe (Start), Bwindi Impenetrable National Park, Bwindi Impenetrable National Park, Entebbe
Uganda · Mountain gorillas · Bwindi focus
Best
Seller
5 Day Gorilla & Chimp Safari
You visit: Entebbe (Start), Kibale National Park, Bwindi Impenetrable National Park, Entebbe (End)
Uganda · Gorillas & habituated chimps
Best
Seller
6 Day Gorillas, Chimps & Wildlife
You visit: Entebbe (Start), Kibale Forest, Queen Elizabeth NP, Bwindi Impenetrable Forest
Uganda · Primates & savannah wildlife
Best
Seller
7 Day Uganda Wildlife & Gorilla
You visit: Entebbe (Start), Murchison Falls NP, Kibale Forest, Queen Elizabeth NP
Uganda · Nile, chimps, wildlife & gorillas
3 Day Murchison Falls Safari
You visit: Entebbe (Start), Murchison Falls NP, Entebbe (End)
Uganda · Nile boat & Big Five potential
10 Day Ultimate Uganda Safari
You visit: Entebbe (Start), Murchison Falls NP, Kibale Forest, Queen Elizabeth NP
Uganda · Extended flagship circuit